Stocks / PFE
PFE stock forecast
PFIZER INC · Healthcare · Drug Manufacturers - General
The model's rating
Greatly Outperform
PFE is rated Greatly Outperform as of September 29, 2026: its medium-term return forecast is in the top fifth of the stocks the model scores.
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PFE is not among the 20 largest holdings published for 2026 Q4. See the portfolio
PFE against the S&P 500
| Period | PFE | S&P 500 (SPY) |
|---|---|---|
| 1 month | +0.2% | -0.3% |
| 3 months | +21.5% | +2.5% |
| Year to date | +20.5% | +12.7% |
| 1 year | +19.8% | +15.7% |
Total return, dividends included.
Key numbers
| Price | $28.52 |
| Market cap | 162.55 Billion |
| P/E (trailing 12 months) | 37.5 |
| P/S (trailing 12 months) | 2.5 |
| P/B (latest quarter) | 1.7 |
| Gross margin | 73.2% |
| Net profit margin | 6.8% |
| Return on equity | 4.9% |
| Beta | 0.3 |
As of August 4, 2026.
PFE and its closest peers
| Stock | Company | Market cap | Model rating | |
|---|---|---|---|---|
| GILD | GILEAD SCIENCES INC | 184.82 Billion | Outperform | GILD vs PFE |
| BMY | BRISTOL MYERS SQUIBB CO | 127.47 Billion | Outperform | PFE vs BMY |
| AMGN | AMGEN INC | 227.88 Billion | Outperform | AMGN vs PFE |
| BIIB | BIOGEN INC | 33.37 Billion | Outperform | PFE vs BIIB |
| MRK | MERCK & CO INC | 358.5 Billion | Greatly Outperform | |
| ABBV | ABBVIE INC | 462.26 Billion | Outperform |
Questions
What does the Upfront Investment model say about PFE?
The model rates PFIZER INC (PFE) "Greatly Outperform" as of September 29, 2026, which means its medium-term return forecast is in the top fifth of the stocks the model scores. The rating is a statistical forecast, not a recommendation to buy or sell.
How is the PFE rating produced?
A machine-learning model forecasts each stock's return over the coming months and ranks the forecasts against each other. The label says where this stock's forecast falls in that ranking. It is refreshed whenever the model's data updates, normally every trading day.
Is PFE in the Upfront Investment model portfolio?
PFE is not among the 20 largest holdings published for 2026 Q4.
The rating is the output of a statistical model and can be wrong. It is not investment advice and takes no account of your circumstances. Past performance does not guarantee future results.